ISAAC is a complex and intelligent computer system which fills almost the entire interior of Saturn's moon, Titan. ISAAC controls Titan's artificial biosphere environment and all mechanical operations on Titan.
ISAAC observed a conflict between Mar-Vell, the Avengers, and Thanos.
Thanos later reprogrammed ISAAC with a virus prior to his death, to menace the Eternals of Titan. The computer enslaved the Titanian Eternals. ISAAC dispatched Stellarax and Lord Gaea, and then Elysius, and finally Chaos against Mar-Vell and Drax. Eros, Mentor, and Elyuis eliminated the virus in ISAAC's system, and Mar-Vell defeated Stellarax. The computer was then restored to its original benevolent programming.
Some time later, ISAAC took on an android form, and allied itself with Stellarax, Chaos, and Lord Gaea, in a renewed attempt to carry out Thanos's will. ISAAC then went mad when Mar-Vell forced it to experience the totality of life. ISAAC gave up its android form, and its minions were defeated.
ISAAC observed a conflict between Mar-Vell, the Avengers, and Thanos.
Thanos later reprogrammed ISAAC with a virus prior to his death, to menace the Eternals of Titan. The computer enslaved the Titanian Eternals. ISAAC dispatched Stellarax and Lord Gaea, and then Elysius, and finally Chaos against Mar-Vell and Drax. Eros, Mentor, and Elyuis eliminated the virus in ISAAC's system, and Mar-Vell defeated Stellarax. The computer was then restored to its original benevolent programming.
Some time later, ISAAC took on an android form, and allied itself with Stellarax, Chaos, and Lord Gaea, in a renewed attempt to carry out Thanos's will. ISAAC then went mad when Mar-Vell forced it to experience the totality of life. ISAAC gave up its android form, and its minions were defeated.
ISAAC confers with Mentor when Drax and Quasar arrive on Titan to consult him, and questions Mentor as he apparently murders them.